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Preparation of alcohols: hydration, hydroboration, Grignard

Alcohols, Phenols and Ethers · Chemistry

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Make 1-propanol from propene. Which route? Step 1: Acid hydration (Markovnikov) → 2-propanol — WRONG isomer! Step 2: Hydroboration–oxidation: B₂H₆ then H₂O₂/OH⁻ → anti-Markovnikov → 1-propanol. Correct! Step 3: Oxymercuration would also give Markovnikov (2-propanol). Step 4: For anti-Markovnikov alcohol, hydroboration is the tool. Choose it!

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