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Pathogenesis of gingivitis and periodontitis

Periodontology · Dental (BDS)

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Two patients have similar plaque levels, but one has severe bone loss and the other has healthy gums. How? The difference is the host response - one person's immune system overreacts, releasing enzymes and signals that activate bone-eating osteoclasts, while the other's stays proportionate. Students learn periodontitis is not a simple infection but a host-mediated disease: bacteria light the fire, the body's own response burns the house.

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