Nephrology: nephrotic syndrome, UTI in children
Pediatrics · MBBS
Study notes
A 4-year-old — puffy face, swelling; heavy proteinuria; minimal change; steroids remit. Nephrotic syndrome (edema — periorbital, heavy proteinuria — >40mg/m²/h, hypoalbuminemia, hyperlipidemia: minimal change — commonest — selective albuminuria — steroid-sensitive — prednisolone 4 weeks daily + 4 alternate; frequent relapsers — levamisole/cyclophosphamide; biopsy — resistant): nephritic (hematuria — cola-colored, hypertension, oliguria — post-streptococcal — ASO — supportive — fluids/salt restrict, antihypertensives). UTI (fever without focus — infants: culture — treat — cephalosporin; investigate — <2yr — USG, MCU — VUR; prophylaxis — recurrent). The puffy face with protein is nephrotic — steroids remit.
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